Lifestyle, Meds, and Surgery: A Combined Approach

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Combining Lifestyle, Medication, and Surgery: A Holistic Approach to Obesity Treatment

In the ever-evolving world of obesity treatment, a comprehensive approach that balances lifestyle changes, medications, and, when necessary, surgery has proven to be the most effective strategy. At the ACP Internal Medicine Meeting 2025, Dr. Laura Davisson, a leading expert in the field, shared invaluable insights into this multifaceted approach, emphasizing the importance of individualized care.

Understanding the Current Landscape of Pharmacologic Treatments

What Are the Leading Weight Loss Medications?

Dr. Davisson explains that today’s clinicians have access to a diverse toolkit for managing obesity, featuring both oral and injectable medication options. Among these, the GLP-1 receptor agonists have emerged as the leading choice for effective weight loss. These medications not only facilitate weight reduction but also enhance metabolic health.

“I emphasized in my talk the significance of understanding the full spectrum of pharmacologic tools available,” she notes, highlighting the importance of individualized treatment plans for each patient.

Managing Common Side Effects of Weight Loss Medications

What Complications Should Patients Anticipate?

One pressing concern associated with GLP-1 medications is their effect on gastric emptying. Dr. Davisson explains that while they can lead to feelings of fullness, they sometimes cause undesirable gastrointestinal side effects such as:

  • Mild nausea
  • Occasional vomiting
  • Constipation

To proactively manage these symptoms, patients can utilize over-the-counter remedies, adjust their diet, and apply simple strategies. With time and continued use, most patients find that these side effects diminish as their bodies adjust.

Interestingly, some patients report experiencing “sulfur burps.” While these can be unpleasant, Dr. Davisson assures that they can be effectively managed with lifestyle tweaks and proactive patient education.

Beyond Medications: The Role of Bariatric Surgery

Why Consider Surgery?

While medications are in the spotlight, it’s crucial not to overlook the long-standing effectiveness of bariatric surgery. According to Dr. Davisson, this option has shown remarkable success in both substantial weight loss and long-term sustainability, especially for individuals with a BMI of 40 or higher.

“Many patients initially hesitate at the thought of surgery,” she shares. However, as they experience the limitations and frustrations of battling obesity biologically, their perspectives often shift. Recognizing obesity as a chronic disease can make them more receptive to surgical options when appropriate.

The Cornerstone of Lifestyle Change

Why Lifestyle Interventions Matter

Ultimately, the foundation of any successful obesity treatment regimen is rooted in lifestyle changes. As Dr. Davisson emphasizes, dietary improvements, increased physical activity, and practical behavioral strategies are essential components for all patients.

For some, lifestyle modifications alone may suffice. However, for the majority, an ideal treatment involves a synergistic approach—blending lifestyle changes with pharmacologic or surgical interventions. This comprehensive strategy yields the most promising results.


In conclusion, the fight against obesity is not one that can be waged by relying solely on medications or interventions. It requires a team-based strategy focused on personalized care that acknowledges the unique needs and preferences of each patient. By combining lifestyle changes, medications, and surgery when necessary, healthcare providers can create tailored solutions that not only promote weight loss but also enhance overall health and well-being.

For further details on obesity treatment options, consider visiting the Obesity Society for a wealth of resources and support.


This engaging narrative not only illuminates the complexities of obesity treatment but also empowers readers to embrace a multifaceted approach for lasting health improvements.

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