This article is part of our Football Predictions series.
**Welcome to Week 13 of the MLS**—a thrilling midweek match-up awaits, promising excitement and golden opportunities for savvy bettors. With matches kicking off at **7:30 p.m. ET on Wednesday**, it’s the perfect time to **place your bets and strategize your parlays.** Let’s dive into the best betting tips and picks for an unforgettable weekend!
Top MLS Week 13 Betting Picks and Predictions
**Must-Bet Parlay: Philadelphia Union & LAFC**
**Why this bet?** After suffering an embarrassing **7-0 defeat to the New York Red Bulls**, the **LA Galaxy** faces another critical challenge as they take on the Philadelphia Union. The Galaxy struggled without star players **[Gabriel Pec](https://www.rotowire.com/soccer/player/gabriel-pec-29701)** and **[Joseph Paintsil](https://www.rotowire.com/soccer/player/joseph-paintsil-29826)**, both sidelined due to injuries.
Meanwhile, the **Philadelphia Union** are on a roll, remaining **unbeaten in their last five matches** and scoring multiple goals in four of those. **LAFC** also boasts an unbeaten streak, with **multiple goals in each of their recent outings**. Given the Galaxy’s struggles and upcoming tough fixtures, it’s tough to envision a bounce-back performance this week.
**Recommended Bet:** Combine **Philadelphia Union Moneyline against LA Galaxy** with **LAFC Draw No Bet** for a sweet parlay at **+133**. If you’re feeling extra bold, consider adding an **LAFC Moneyline** for a juicy payout of **+303**!
*Check out the latest MLS odds at the DraftKings Sportsbook. If you’re not signed up, visit our DraftKings promo code page for exclusive bonuses!
Major League Soccer Best Bets
**Smart Parlay: Austin FC vs. Atlanta United**
With just **four goals in their last seven matches**, **Austin FC** is struggling to find the back of the net. In contrast, **Atlanta United** has scored only **three times in their last six games**. Therefore, betting on **Under 5 Goals** could bring solid returns. If you want to amplify your payout, consider lowering the threshold to **Under 4 Goals**, which could push your odds to **+202**!
*MLS odds are live at BetMGM. Use the BetMGM bonus code ROTOBONUS for a risk-free bet and enhance your betting experience!
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MLS Betting Picks for Wednesday, May 14
- Parlay: Philadelphia Union Moneyline (vs. LA Galaxy) & LAFC Draw No Bet (vs. LA Galaxy) +133
- Parlay: Philadelphia Union Moneyline (vs. LA Galaxy) & LAFC Moneyline (vs. LA Galaxy) +303
- 3-Leg Parlay: Austin FC vs. Atlanta United Under 5 Goals + Philadelphia Union or Tie (Double Chance) + LAFC Draw No Bet +145
- 3-Leg Parlay: Austin FC vs. Atlanta United Under 4 Goals + Philadelphia Union or Tie (Double Chance) + LAFC Draw No Bet +202
Stay tuned with RotoWire throughout the season for exclusive sports betting picks and our weekly Kits & Wagers betting show. For the best lines, explore our odds page, featuring competitive odds from FanDuel, PointsBet, and more. Unlock over a thousand dollars in bonuses by signing up at the best sports betting sites using the best sportsbook promos.